The October 2016 Windows security updates appears to have come bearing gifts for SCOM Admins this year. These surfaced in the form of specific OS updates that appear to crash SCOM consoles across various server OS versions. Microsoft has identified the culprit updates as certain Windows security updates KB3194798/3192392/3185330/3185331 and it would seem that consoles installed on Server 2008R2 through 2016 are affected. I’ve seen various faulting modules referenced throughout out the community with ntdll.dll appearing to be one of the main ones out there. In my case, I see an additional issue with the ieframe.dll as seen below.
UPDATE: HOTFIX Released.
The product group released a hotfix for this issue and Security Update for Microsoft Windows (KB3200006) appears to correct the problem on all affected OS Server versions. You can read the official post about this issue here.